Turn Promising Discoveries into
Viable Drug Candidates
Our Pre-Formulation Services evaluate the developability of molecules at the earliest stage of pharmaceutical development.
By characterizing the physical, chemical, and mechanical properties of new drug substances, we help identify
potential challenges such as solubility, stability, and bioavailability and define clear strategies
for efficient downstream development.
What We Do
At Sortis Pharma, our pre-formulation capabilities are designed to deliver comprehensive profiling of molecules to
support formulation design and development planning. Our advanced laboratories perform detailed assessments that
help you save time, reduce material waste, and make data-driven decisions for future stages of development
Comprehensive Molecule Profiling
Our scientific team performs structured evaluations of key material attributes, including:
- Solid-state form and stability
- Solubility behavior across pH and biorelevant media
- Thermal and moisture interactions
- Degradation under stress conditions
This early characterization helps identify risks and establish a strong scientific foundation for formulation and process development.
Solid-State Optimization
Our solid-state experts focus on addressing performance issues related to polymorphism, crystal form, and material properties that can affect stability and manufacturability. Services include:
- Crystallization and salt selection
- Co-crystal and polymorph screening
- Solid form scale-up and process development
Choosing the right solid form early drives better stability, process performance, and bioavailability in later stages.
Innovative Formulation Solutions
To support a broad range of development goals, we also offer tailored formulation strategies that complement pre-formulation insights. These include approaches designed to enhance bioavailability or support specific delivery routes such as:
- Oral systems including suspensions, nanosuspensions, and solid dispersions
- Injectables such as solutions and lyophilized
- Topical and ophthalmic formulations including creams, gels, and eye drops
All formulation solutions are planned with scalability in mind, ensuring a smooth transition from lab to clinical stages.
Building a strong scientific foundation for
pharmaceutical development
Scientific Understanding
Pre-formulation studies provide critical insight into the physicochemical behavior of drug substances, supporting informed formulation decisions.
Informed Formulation Strategy
Early characterization data helps define appropriate formulation approaches, process feasibility, and development pathways.
Quality & Development Readiness
Structured pre-formulation activities support data integrity, documentation quality, and alignment with development expectations.
Risk Reduction & Efficiency
Identifying potential challenges early helps reduce development risk, minimize rework, and support efficient progression.
Looking for a Trusted Pharmaceutical Partner?
Let’s discuss how our pharmaceutical capabilities can support your requirements.